Peptide Library / Detail
Palmitoyl Tetrapeptide-7
Half-life
Not applicable for topical administration; remains active in skin tissue for several hours following application
Delivery
Topical application in cosmetic formulations; experimental injectable hydrogel delivery systems under research
Dosage
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Description
Palmitoyl Tetrapeptide-7 is a synthetic peptide consisting of four amino acids attached to palmitic acid, designed to mimic the action of immunoglobulin G (IgG). It is widely used in cosmetic formulations to reduce inflammation and improve skin appearance. This peptide is particularly valued for its application in anti-aging and sensitive skin care products.
Usage
Typically applied topically in cosmetic formulations at concentrations ranging from 2-10 ppm (parts per million). Commonly incorporated into serums, creams, and other skincare products designed for daily use. Often combined with other peptides such as palmitoyl oligopeptide for enhanced effects. Products are generally applied once or twice daily to clean skin.
Mechanism of Action
Palmitoyl Tetrapeptide-7 functions by modulating inflammatory responses in the skin, specifically reducing interleukin-6 (IL-6) production. It acts on fibroblasts to decrease excessive immune responses that contribute to skin aging and sensitivity. The peptide helps regulate the extracellular matrix by influencing collagen and elastin metabolism, thereby supporting dermal-epidermal junction integrity and reducing age-related structural deterioration.
Benefits(7)
- Reduces inflammation and inflammatory markers in skin tissue
- Improves extracellular matrix composition and dermal structure
- Enhances epidermal-dermal junction integrity
- Reduces visible signs of skin aging and photoaging
- Suitable for sensitive skin applications
- Promotes wound healing and tissue regeneration when combined with delivery systems
- Decreases skin roughness and improves overall texture
Side Effects(4)
- Minimal reported adverse effects in topical applications
- Potential mild skin irritation in sensitive individuals
- Rare allergic reactions to formulation components
- Possible temporary redness at application site