SS-31

SS-31 — frequently asked questions

• What is SS-31?

  SS-31 (also known as Elamipretide or Bendavia) is a synthetic tetrapeptide that selectively targets cardiolipin on the inner mitochondrial membrane to improve mitochondrial function and reduce oxidative stress.

• What is the half-life of SS-31?

  SS-31 has an approximate half-life of ≈2 hours. The half-life determines how often you need to inject to maintain steady blood levels — use the Peptides Calculator half-life calculator to plot your specific dosing schedule and see the decay curve.

• How is SS-31 administered?

  SS-31 is typically delivered via subcutaneous or intravenous injection. The Peptides Calculator app helps you reconstitute the vial with bacteriostatic water, calculate your exact dose in syringe units, and track each injection.

• How does SS-31 work?

  Binds to cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure, enhancing electron transport chain efficiency, reducing reactive oxygen species production, and preventing cytochrome c peroxidase activity.

• What are the researched benefits of SS-31?

  Studied benefits of SS-31 include: Improved mitochondrial bioenergetics, Reduced reactive oxygen species (ROS) production, Protection against ischemia-reperfusion injury, Improved cardiac and skeletal muscle function, Neuroprotective effects in models of neurodegeneration. These are research findings only — Peptides Calculator does not provide medical advice; consult a qualified healthcare professional before starting any peptide protocol.

• What are the side effects of SS-31?

  Reported side effects of SS-31 include: Injection-site reactions, Nausea, Headache, Possible mild hypotension. Always discuss potential side effects with a licensed healthcare provider before using any research peptide.