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Vial

HMG (Human Menopausal Gonadotropin)

Gonadotropin (FSH/LH blend)For research use only
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HMG, also called menotropins, provides both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) bioactivity. In research settings, it’s used to stud…

Half-life

Approximate: FSH activity ~24–36 hours; LH activity ~10–20 hours (route- and product-dependent).

Delivery

Subcutaneous or intramuscular injection

Suggested dosage

Not specified

Usage

Investigated for inducing follicular development, supporting spermatogenesis, and modeling endocrine feedback in the hypothalamic–pituitary–gonadal (HPG) axis.

Mechanism of action

FSH component activates FSH receptors in gonadal tissue to promote follicular growth and Sertoli-cell–mediated spermatogenesis. LH component activates LH/CG receptors to stimulate theca/Leydig cell steroidogenesis (estradiol/testosterone).

Benefits (4)

  • Stimulates follicular development (ovary)
  • Supports spermatogenesis (testis)
  • Increases gonadal steroid production
  • Useful for HPG-axis functional studies

Side effects (6)

  • Injection-site pain or redness
  • Abdominal discomfort/bloating
  • Headache or mood changes
  • Fluid retention
  • Gynecomastia (males)
  • Ovarian hyperstimulation–like effects in susceptible models
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