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Vial

MGF (Mechano Growth Factor, IGF-1Ec)

IGF-1 Splice Variant (Local Repair Peptide)For research use only
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MGF is the IGF-1Ec splice variant expressed in response to mechanical overload. As a short, locally acting peptide, it’s studied for activating muscle satellite…

Half-life

Very short (on the order of minutes, often cited ~5–7 min) with primarily local action

Delivery

Local intramuscular or perilesional microinjections near the target muscle immediately post-session/injury in research protocols.

Suggested dosage

Not specified

Usage

Investigated for post-exercise or post-injury muscle regeneration, myoblast activation, and localized tissue repair models.

Mechanism of action

Acts in an autocrine/paracrine manner to upregulate satellite-cell activation and proliferation, modulate myogenic regulatory factors, and initiate early-stage muscle repair distinct from systemic IGF-1 signaling.

Benefits (4)

  • Promotes satellite cell activation and proliferation
  • Supports localized muscle repair/remodeling
  • May reduce recovery time after mechanical stress
  • Complements later-stage IGF-1–mediated hypertrophy pathways

Side effects (4)

  • Injection-site redness or irritation
  • Transient localized swelling/pump sensation
  • Rare dizziness or fatigue
  • Theoretical risk of disproportionate tissue growth with improper use
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