Peptide Library / Detail
MGF (Mechano Growth Factor, IGF-1Ec)
Half-life
Very short (on the order of minutes, often cited ~5–7 min) with primarily local action
Delivery
Local intramuscular or perilesional microinjections near the target muscle immediately post-session/injury in research protocols.
Dosage
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Research Use Only
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Description
MGF is the IGF-1Ec splice variant expressed in response to mechanical overload. As a short, locally acting peptide, it’s studied for activating muscle satellite cells, promoting repair, and remodeling damaged tissue.
Usage
Investigated for post-exercise or post-injury muscle regeneration, myoblast activation, and localized tissue repair models.
Mechanism of Action
Acts in an autocrine/paracrine manner to upregulate satellite-cell activation and proliferation, modulate myogenic regulatory factors, and initiate early-stage muscle repair distinct from systemic IGF-1 signaling.
Benefits(4)
- Promotes satellite cell activation and proliferation
- Supports localized muscle repair/remodeling
- May reduce recovery time after mechanical stress
- Complements later-stage IGF-1–mediated hypertrophy pathways
Side Effects(4)
- Injection-site redness or irritation
- Transient localized swelling/pump sensation
- Rare dizziness or fatigue
- Theoretical risk of disproportionate tissue growth with improper use