Peptide Library / Detail
Hexarelin
Half-life
60-90 minutes
Delivery
Subcutaneous injection
Dosage
—
Research Use Only
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Description
Hexarelin is a synthetic hexapeptide and potent growth hormone secretagogue that belongs to the GHRP family. It stimulates growth hormone release from the pituitary gland with greater potency than earlier peptides like GHRP-6. Hexarelin has been studied for its effects on growth hormone production, cardiac function, and body composition.
Usage
Research protocols typically use 100-200 mcg per dose, administered 2-3 times daily via subcutaneous injection. Doses are commonly taken on an empty stomach, with at least 30 minutes before meals for optimal absorption. Cycling protocols of 8-12 weeks followed by breaks are often implemented to prevent desensitization.
Mechanism of Action
Hexarelin acts as a ghrelin mimetic, binding to the growth hormone secretagogue receptor (GHS-R1a) in the pituitary gland and hypothalamus. This binding triggers a cascade that results in growth hormone release. Additionally, it demonstrates cardioprotective effects through GHS-R receptors in cardiac tissue, potentially improving ventricular function and protecting against ischemic damage independent of growth hormone effects.
Benefits(7)
- Potent stimulation of growth hormone release
- Improved muscle mass and strength development
- Enhanced fat metabolism and body composition
- Potential cardioprotective properties
- Increased bone mineral density
- Improved recovery and tissue repair
- May enhance collagen synthesis
Side Effects(7)
- Increased appetite and hunger
- Water retention and bloating
- Temporary fatigue or lethargy
- Numbness or tingling in extremities
- Elevated cortisol and prolactin levels
- Potential desensitization with prolonged use
- Joint discomfort in some users