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SS-31

Mitochondria-Targeted Peptide

SS-31 (also known as Elamipretide or Bendavia) is a synthetic tetrapeptide that selectively targets cardiolipin on the inner mitochondrial membrane to improve mitochondrial function and reduce oxidative stress.

Usage:

Used in research on mitochondrial dysfunction, ischemia-reperfusion injury, heart failure, neurodegenerative diseases, and age-related decline in bioenergetics.

Mechanism of Action:

Binds to cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure, enhancing electron transport chain efficiency, reducing reactive oxygen species production, and preventing cytochrome c peroxidase activity.

Benefits:

  • Improved mitochondrial bioenergetics
  • Reduced reactive oxygen species (ROS) production
  • Protection against ischemia-reperfusion injury
  • Improved cardiac and skeletal muscle function
  • Neuroprotective effects in models of neurodegeneration

Side Effects:

  • Injection-site reactions
  • Nausea
  • Headache
  • Possible mild hypotension

Suggested Dosage:

Not specified

Half-life: ≈2 hours

Delivery: Subcutaneous or intravenous injection

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