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Glutathione
Tripeptide Antioxidant
Glutathione is a tripeptide composed of glutamate, cysteine, and glycine; it serves as the body's principal endogenous antioxidant and detoxifier.
Usage:
Used in research to study oxidative stress, detoxification pathways, immune function, and skin health.
Mechanism of Action:
Acts as an electron donor to neutralize reactive oxygen species and participates in phase II detoxification by conjugating to xenobiotics via glutathione S-transferases.
Benefits:
- Reduction of oxidative stress
- Support for phase II detoxification
- Enhanced immune cell function
- Potential skin-brightening effects
Side Effects:
- Generally well tolerated
- High oral doses may cause gastrointestinal discomfort
- Rare allergic reactions
Suggested Dosage:
Not specified
Half-life: ≈1.5–2 hours (intravenous); oral bioavailability is low and variable
Delivery: Oral, liposomal, intravenous, or intramuscular injection