Peptide Library / Detail
Thymagen
Half-life
30-60 minutes
Delivery
Subcutaneous or intramuscular injection
Dosage
—
Research Use Only
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Description
Thymagen is a synthetic thymic peptide bioregulator consisting of the dipeptide Lys-Glu (lysine-glutamic acid). It is designed to support immune system function by modulating thymus gland activity and lymphocyte function. Thymagen belongs to the class of short peptide bioregulators developed for immune system support and restoration.
Usage
Research protocols typically involve subcutaneous or intramuscular administration at dosages ranging from 10-20 mg per day or every other day. Cycles generally run 10-20 days with periodic breaks. Some protocols suggest administration in the evening for optimal thymic hormone activity alignment.
Mechanism of Action
Thymagen works by modulating cyclic nucleotide metabolism in immune cells, specifically affecting cAMP and cGMP levels in spleen lymphocytes and influencing phosphodiesterase activity. Research by Demidov et al. (1991) demonstrated its effects on second messenger systems during immune sensitization and anaphylactic responses. It appears to support thymic function and promote homeostatic regulation of T-cell populations.
Benefits(6)
- Supports immune system function and responsiveness
- Modulates lymphocyte cyclic nucleotide levels
- May help restore thymic function with aging
- Potential protective effects during allergic responses
- Supports T-cell population regulation
- May enhance immune recovery after stress or illness
Side Effects(5)
- Injection site reactions (redness, swelling)
- Mild headache
- Transient fatigue
- Rare allergic reactions
- Potential immune system overstimulation in susceptible individuals