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LL‑37 (5 mg)
Antimicrobial Peptide
LL‑37 is a human cathelicidin antimicrobial peptide that serves as part of the innate immune system with broad-spectrum antimicrobial, immunomodulatory, and tissue repair functions.
Usage:
Used in research on innate immunity, antimicrobial activity, wound healing, angiogenesis, and immunomodulation.
Mechanism of Action:
Positively charged amphipathic peptide that binds to microbial membranes, forming pores to induce lysis; modulates immune cell chemotaxis, cytokine release, and wound healing pathways.
Benefits:
- Potent antimicrobial against bacteria, viruses, and fungi
- Promotes wound healing and angiogenesis
- Immunomodulatory: chemotactic, anti-/pro-inflammatory depending on context
- Resistant to proteolytic degradation
Side Effects:
- Cytotoxic to mammalian cells at high concentrations
- Potential pro-inflammatory or autoimmune activation in certain contexts
Suggested Dosage:
Not specified
Half-life:
Delivery: Lyophilized powder—reconstitute in sterile bacteriostatic water for in vitro or preclinical use