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Epitalon
Tetrapeptide
Epitalon (also known as epithalon or epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the bovine pineal gland extract epithalamin, studied for its ability to activate telomerase and exert geroprotective effects.
Usage:
Used in research on aging, telomere lengthening, antioxidant defense, mitochondrial function, and immune modulation.
Mechanism of Action:
Upregulates telomerase reverse transcriptase expression and telomerase activity in somatic cells, promotes heterochromatin decondensation, and modulates antioxidant enzyme activity and mitochondrial health.
Benefits:
- Telomere elongation and surpassing the Hayflick limit in cell cultures
- Reduction of oxidative stress via increased SOD and GPx activities
- Improved mitochondrial membrane potential and function
- Enhanced immune cell proliferation and function
- Potential oncostatic and anti-metastatic effects in animal models
Side Effects:
- Minimal adverse effects reported in preclinical and limited clinical studies
- Possible mild injection-site irritation
Suggested Dosage:
Not specified
Half-life: 30 minutes
Delivery: Subcutaneous injection