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Vial

Epitalon

Tetrapeptide

Epitalon (also known as epithalon or epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the bovine pineal gland extract epithalamin, studied for its ability to activate telomerase and exert geroprotective effects.

Usage:

Used in research on aging, telomere lengthening, antioxidant defense, mitochondrial function, and immune modulation.

Mechanism of Action:

Upregulates telomerase reverse transcriptase expression and telomerase activity in somatic cells, promotes heterochromatin decondensation, and modulates antioxidant enzyme activity and mitochondrial health.

Benefits:

  • Telomere elongation and surpassing the Hayflick limit in cell cultures
  • Reduction of oxidative stress via increased SOD and GPx activities
  • Improved mitochondrial membrane potential and function
  • Enhanced immune cell proliferation and function
  • Potential oncostatic and anti-metastatic effects in animal models

Side Effects:

  • Minimal adverse effects reported in preclinical and limited clinical studies
  • Possible mild injection-site irritation

Suggested Dosage:

Not specified

Half-life: 30 minutes

Delivery: Subcutaneous injection